TEDS Data Dictionary

TEDS Polygenic Scores

Contents of this page:

Introduction

Polygenic score variables now form part of the TEDS dataset. Each polygenic score is derived from genotypic data but relates to a specific phenotypic trait. A polygenic score is a numeric variable derived from multiple measurements of variation at different positions within the genome, taking account of their predictive power in relation to the given phenotypic trait.

The polygenic scores are derived from the TEDS twin genotypic dataset, which is briefly described on the DNA and genotyping studies page. As described on that page, this is a combined OEE + Affymetrix genotype dataset, giving the maximum possible sample size for TEDS twins with available data. The sample comprises 10,346 individual twins, including 3320 genotyped twin pairs (all DZ) and 3706 unpaired twins (mainly MZ but also some DZ). Hence, the sample includes a total of 7026 unrelated twins (one per pair).

This page includes a tabulated list of polygenic scores that have been derived for the TEDS twins and that are available for researchers to use in analysis. There is also a description of the polygenic score variables, and a summary of covariates that are typically used alongside the polgenic scores.

Detailed descriptions of the construction of the genotypic dataset and the derivation of the polygenic scores are beyond the scope of this page. However, links to relevant papers are provided below - essential technical details may be found in the on line supplements for these papers. These papers should also be cited in publications based on results of analysis of the TEDS polygenic scores.

  1. Genotype processing, QC, imputation and harmonisation of the dataset (see paper supplement):
    Selzam, McAdams et al (2018). Evidence for gene-environment correlation in child feeding: Links between common genetic variation for BMI in children and parental feeding practices. PLoS genetics, 14(11), e1007757,
    DOI: 10.1371/journal.pgen.1007757
  2. Calculation of polygenic scores with LDpred (see paper supplement):
    Selzam, Ritchie et al (2019). Comparing Within-and Between-Family Polygenic Score Prediction. American Journal of Human Genetics, 105(2), 351-363,
    DOI: 10.1016/j.ajhg.2019.06.006

Please note that the polygenic score data is the raw LDpred output variable, and is not adjusted for any covariates. The polygenic scores should be adjusted for these covariates (ancestry PCs and chip) using the regression method, and z-standardised prior to further analysis.

Covariates

The polygenic scores should be analysed alongside a set of covariates. As mentioned above, each polygenic score should be adjusted for these covariates (ancestry PCs and chip) using the regression method, and z-standardised prior to further analysis. These covariate variables are listed in the table below.

Covariate variable name(s) Values Description
PC1, PC2, PC3, PC4, PC5, PC6, PC7, PC8, PC9, PC10 Continuously variable, decimal numeric values. The values are both positive and negative, with mean 0 for each variable. The standard deviation is roughly 0.01 for each variable. The distributions are normal. These are the first 10 principal components of the genotype data. These are typically used to make corrections for population stratification (ancestry) in analysis.
Chip String values: 'affy' and 'oee' Denotes the type of chip on which the twin's DNA was genotyped (Affymetrix or OEE)
Batch String values: 'affy', 'bt1', 'bt2', 'bt3', 'bt4', 'bt5, 'bt6', 'btDZ' Denotes the batch in which the twin's DNA was genotyped. The Affymetrix genotyping ('affy') was carried out at the Sanger Institute, and we assume there was a single batch as we do not have batch metadata. The OEE genotyping was carried out at KCl in six main batches for unrelated twins ('bt1' to 'bt6') plus a further batch for genotyped DZ co-twins ('btDZ').
DZ_twin Numeric integer values: 0, 1 Denotes whether the twin was one of a genotyped DZ twin pair: 1=yes, 0=no.
DZ_random_select Numeric integer values: 0, 1 This variable is used to filter the sample of unrelated twins, by selecting each unpaired genotyped twin plus one randomly-selected twin from each genotyped DZ twin pair. Filter on value 0 for the 7,026 unrelated twins.

Polygenic score variables

Each polygenic score is available in the form of three variables, computed using three different thresholds (see links above for details of computation):

ThresholdVariable name suffix
0.01 FRCT0.01
0.3 FRCT0.3
1 FRCT1

Each polygenic score variable has decimal numeric values, which may be positive or negative. The variables are not standardised, so the means, standard deviations and ranges vary from one polygenic score to another. The values vary continuously and are normally distributed.

The polygenic scores are raw, and have not been adjusted for the ancestry principle components (see covariates above). This adjustment will typically need to be done by the researcher, prior to analysis.

The variable prefix is generally the same as the prefix of the name of the raw file from which the score was taken; this filename in turn is derived from the filename of the summary stats that were used in the computation of the score. These names are descriptive of the trait and of the source of the summary stats. Because the names are descriptive, and because they can be referenced using the table below, the variables have not been given variable labels in the dataset.

For example, for the ADHD polygenic score derived from the file called "ADHD_PGC2017_GPS_3T.txt", the three polygenic score variables are named ADHD_PGC2017_FRCT0.01, ADHD_PGC2017_FRCT0.3 and ADHD_PGC2017_FRCT1.

In some cases, where the original filenames were very long, the names have been abbreviated for the purpose of variable naming. Where this has been done, the table below shows both the original file name and the abbreviated variable name prefix.

Data sharing

Please refer to the TEDS data access policy on the main TEDS web site.

The list below includes all available polygenic scores in TEDS, and any of these may be requested within a collaborator data request.

Any given polygenic score will be made available for sharing at the thresholds described above, and not at other thresholds. Similarly, only those covariates described above will be shared alongside the polygenic scores. New polygenic scores that are not listed below, or variations on the listed scores, will not normally be made available to external collaborators.

Polygenic scores list

In the table below, polygenic scores are sorted in ascending alphabetical order of trait category, then trait, then variable name.

As well as scrolling and searching alphabetically, you can use your web browser's search facilities (Ctrl+F) to search for key words.

Trait category: Anthropometric
Trait: balding Pattern 2
Variable name: Hair_balding_pattern_2_2395_NealeUKB2019
Number of SNPs coordinated: 433063
Sample size: 165649 (38044 cases, 127605 controls)
Published study: Neale Lab
Publication year: 2019

Trait category: Anthropometric
Trait: balding Pattern 3
Variable name: Hair_balding_pattern_3_2395_NealeUKB2019
Number of SNPs coordinated: 433063
Sample size: 165649 (44304 cases, 121345 controls)
Published study: Neale Lab
Publication year: 2019

Trait category: Anthropometric
Trait: balding Pattern 4
Variable name: Hair_balding_pattern_4_2395_NealeUKB2019
Number of SNPs coordinated: 433063
Sample size: 165649 (30225 cases, 135424 controls)
Published study: Neale Lab
Publication year: 2019

Trait category: Anthropometric
Trait: Birth weight
Variable name: BirthWeight_EGG2016_GPS
Number of SNPs coordinated: 499994
Sample size: 143677
Published study: https://www.nature.com/articles/nature19806
Publication year: 2016

Trait category: Anthropometric
Trait: BMI
Variable name: BMI_Locke2015_GPS
Number of SNPs coordinated: 451611
Sample size: 339224
Published study: http://www.nature.com/nature/journal/v518/n7538/full/nature14177.html
Publication year: 2015

Trait category: Anthropometric
Trait: BMI
Variable name: Body_mass_index_BMI_21001_UKB2017_GPS
Number of SNPs coordinated: 499425
Sample size: 337199
Published study: http://www.nealelab.is/uk-biobank
Publication year: 2017

Trait category: Anthropometric
Trait: BMI
Variable name: BMI_GIANT2018_GPS
Number of SNPs coordinated: 424816
Sample size: 681275
Published study: https://www.biorxiv.org/content/early/2018/03/02/274654
Publication year: 2018
Note: summary stats formatted because LDpred cannot handle very small pvalues (pval less than 0.000000001 recoded as 0.000000001)

Trait category: Anthropometric
Trait: Childhood obesity
Variable name: ChildObesity_EGG2012_GPS
Number of SNPs coordinated: 449792
Sample size: 13848 (5530 cases, 8318 controls)
Published study: https://www.nature.com/articles/ng.2247
Publication year: 2012

Trait category: Anthropometric
Trait: ICV
Variable name: ICV_Hibar2015_GPS
Number of SNPs coordinated: 497525
Sample size: 30717
Published study: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4393366/
Publication year: 2015

Trait category: Anthropometric
Trait: Infant head circumference
Variable name: HeadCircum_EGG2012_GPS
Number of SNPs coordinated: 450869
Sample size: 10678
Published study: https://www.nature.com/articles/ng.2238
Publication year: 2012

Trait category: Anthropometric
Trait: Mean Caudate
Variable name: MeanCaudate_Hibar2015_GPS
Number of SNPs coordinated: 497525
Sample size: 30717
Published study: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4393366/
Publication year: 2015

Trait category: Anthropometric
Trait: Mean Hippocampus
Variable name: MeanHippocampus_Hibar2015_GPS
Number of SNPs coordinated: 497525
Sample size: 30717
Published study: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4393366/
Publication year: 2015

Trait category: Anthropometric
Trait: Mean Pallidum
Variable name: MeanPallidum_Hibar2015_GPS
Number of SNPs coordinated: 497525
Sample size: 30717
Published study: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4393366/
Publication year: 2015

Trait category: Anthropometric
Trait: Mean Putamen
Variable name: MeanPutamen_Hibar2015_GPS
Number of SNPs coordinated: 497525
Sample size: 30717
Published study: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4393366/
Publication year: 2015

Trait category: Anthropometric
Trait: Mean Thalamus
Variable name: MeanThalamus_Hibar2015_GPS
Number of SNPs coordinated: 497525
Sample size: 30717
Published study: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4393366/
Publication year: 2015

Trait category: Anthropometric
Trait: Standing Height
Variable name: Standing_height_50_UKB2017_GPS
Number of SNPs coordinated: 499422
Sample size: 337199
Published study: http://www.nealelab.is/uk-biobank
Publication year: 2017

Trait category: Anthropometric
Trait: Standing Height
Variable name: Height_GIANT2018_GPS
Number of SNPs coordinated: 427030
Sample size: 693529
Published study: https://www.biorxiv.org/content/early/2018/03/02/274654
Publication year: 2018

Trait category: Anthropometric
Trait: Waist-to-hip ratio
Variable name: WHR_Shungin2015_GPS
Number of SNPs coordinated: 451380
Sample size: 224459
Published study: https://www.ncbi.nlm.nih.gov/pubmed/25673412
Publication year: 2015

Trait category: Behavioural
Trait: Alcohol intake frequency
Variable name: alcohol_intake_frequency_1558_UKB2017_GPS
Number of SNPs coordinated: 499422
Sample size: 336965
Published study: http://www.nealelab.is/blog/2017/7/19/rapid-gwas-of-thousands-of-phenotypes-for-337000-samples-in-the-uk-biobank
Publication year: 2017

Trait category: Behavioural
Trait: Alcohol: former alcohol drinker
Variable name: former_alcohol_drinker_3731_UKB2017_GPS
Number of SNPs coordinated: 499422
Sample size: 21894 (11518 cases, 10376 controls)
Published study: NA
Publication year: 2017

Trait category: Behavioural
Trait: Risk - Automobile speading
Variable name: Risk_AutoSpeeding_Linner2019_GPS
Number of SNPs coordinated: 500760
Sample size: 404291
Published study: https://www.ncbi.nlm.nih.gov/pubmed/30643258
Publication year: 2019

Trait category: Behavioural
Trait: Risk - Drinks per week
Variable name: Risk_DrinksAWeek_Linner2019_GPS
Number of SNPs coordinated: 500760
Sample size: 414343
Published study: https://www.ncbi.nlm.nih.gov/pubmed/30643258
Publication year: 2019

Trait category: Behavioural
Trait: Risk - Ever smoker
Variable name: Risk_EverSmoker_Linner2019_GPS
Number of SNPs coordinated: 500760
Sample size: 518633
Published study: https://www.ncbi.nlm.nih.gov/pubmed/30643258
Publication year: 2019

Trait category: Behavioural
Trait: Risk - First PC from automobile speading, drinks per week, ever smoker, sexual partners
Variable name: Risk_PC1_Linner2019_GPS
Number of SNPs coordinated: 500760
Sample size: 315894
Published study: https://www.ncbi.nlm.nih.gov/pubmed/30643258
Publication year: 2019

Trait category: Behavioural
Trait: Risk - Risk tolerance
Variable name: Risk_RiskTolerance_Linner2019_GPS
Number of SNPs coordinated: 500760
Sample size: 466571
Published study: https://www.ncbi.nlm.nih.gov/pubmed/30643258
Publication year: 2019

Trait category: Behavioural
Trait: Risk - Sexual partners
Variable name: Risk_NumberSexualPartners_Linner2019_GPS
Number of SNPs coordinated: 500760
Sample size: 370711
Published study: https://www.ncbi.nlm.nih.gov/pubmed/30643258
Publication year: 2019

Trait category: Behavioural
Trait: Smoking: age smoking initiation
Variable name: Age_of_smoking_TAG2010_GPS
Number of SNPs coordinated: 450936
Sample size: 47961
Published study: http://www.ncbi.nlm.nih.gov/pubmed/20418890
Publication year: 2010

Trait category: Behavioural
Trait: Smoking: cigarettes per day
Variable name: CPD_TAG2010_GPS
Number of SNPs coordinated: 451117
Sample size: 68028
Published study: http://www.ncbi.nlm.nih.gov/pubmed/20418890
Publication year: 2010

Trait category: Behavioural
Trait: Smoking: current tobacco smoking
Variable name: current_tobacco_smoking_1239_UKB2017_GPS
Number of SNPs coordinated: 499422
Sample size: 337030
Published study: NA
Publication year: 2017

Trait category: Behavioural
Trait: Smoking: ever smoked
Variable name: Ever_smoking_TAG2010_GPS
Number of SNPs coordinated: 450973
Sample size: 74035
Published study: http://www.ncbi.nlm.nih.gov/pubmed/20418890
Publication year: 2010

Trait category: Behavioural
Trait: Smoking: ever smoked
Variable name: ever_smoked_20160_UKB2017_GPS
Number of SNPs coordinated: 499422
Sample size: 336067 (202585 cases, 133482 controls)
Published study: NA
Publication year: 2017

Trait category: Behavioural
Trait: Smoking: ex-smokers
Variable name: tobacco_smoking_exsmoker_22506_113_UKB2017_GPS
Number of SNPs coordinated: 499422
Sample size: 83133 (30184 cases, 52949 controls)
Published study: NA
Publication year: 2017

Trait category: Behavioural
Trait: Smoking: number of cigarettes currently smoked daily (current cigarettes smokers)
Variable name: cigarette_smoked_daily_3456_UKB2017_GPS
Number of SNPs coordinated: 499422
Sample size: 23205
Published study: NA
Publication year: 2017

Trait category: Behavioural
Trait: Smoking: number of cigarettes reviously smoked daily
Variable name: cigarette_smoked_daily_previously_2887_UKB2017_GPS
Number of SNPs coordinated: 499422
Sample size: 78291
Published study: NA
Publication year: 2017

Trait category: Behavioural
Trait: Smoking: pack years
Variable name: pack_years_smoking_20161_UKB2017_GPS
Number of SNPs coordinated: 499422
Sample size: 101726
Published study: NA
Publication year: 2017

Trait category: Behavioural
Trait: Smoking: pack years smoking as proportion of lifespan exposed to smoking
Variable name: pack_years_smoking_20162_UKB2017
Number of SNPs coordinated: 499422
Sample size: 101726
Published study: NA
Publication year: 2017

Trait category: Behavioural
Trait: Smoking: past tobacco smoking
Variable name: past_tobacco_smoking_1249_UKB2017_GPS
Number of SNPs coordinated: 499422
Sample size: 310749
Published study: NA
Publication year: 2017

Trait category: Behavioural
Trait: Time spent at the computer
Variable name: time_spent_computer_1080_UKB2017_GPS
Number of SNPs coordinated: 499422
Sample size: 261987
Published study: NA
Publication year: 2017

Trait category: Behavioural
Trait: Time spent watching TV
Variable name: time_spent_watching_tv_1070_UKB2017_GPS
Number of SNPs coordinated: 499422
Sample size: 319740
Published study: NA
Publication year: 2017

Trait category: Cognitive
Trait: Childhood Intelligence
Variable name: ChildIQ_CHIC2014_GPS
Number of SNPs coordinated: 450966
Sample size: 15164
Published study: https://www.ncbi.nlm.nih.gov/pubmed/23358156
Publication year: 2014
Note: GWAS re-run after excluding TEDS IDs in discovery sample

Trait category: Cognitive
Trait: Fluid intelligence score
Variable name: fluid_intelligence_score_20016_UKB2017_GPS
Number of SNPs coordinated: 499422
Sample size: 108818
Published study: NA
Publication year: 2017

Trait category: Cognitive
Trait: Intelligence (IQ3)
Variable name: IQ_Savage2018_GPS
Number of SNPs coordinated: 497059
Sample size: 266453
Published study: https://www.nature.com/articles/s41588-018-0152-6
Publication year: 2018
Note: Sample excludes TEDS individuals and the two dbGaP datasets due to some issues

Trait category: Cognitive
Trait: Intelligence (IQ3) incl TEDS
Variable name: IQ_Savage2018_inclTEDS_GPS
Number of SNPs coordinated: 512620
Sample size: 269867
Published study: https://www.nature.com/articles/s41588-018-0152-6
Publication year: 2018
Note: Sample includes TEDS participants

Trait category: Cognitive
Trait: Years of Education (EA2)
Variable name: EA2_Okbay2016_GPS
Number of SNPs coordinated: 499944
Sample size: 328918
Published study: https://www.nature.com/articles/nature17671
Publication year: 2016

Trait category: Cognitive
Trait: Years of Education (EA3)
Variable name: EA3_Lee2018_no23andme_GPS
Number of SNPs coordinated: 496633
Sample size: 766345
Published study: https://www.nature.com/articles/s41588-018-0147-3
Publication year: 2018

Trait category: Mental Health
Trait: ADHD
Variable name: ADHD_PGC2012_GPS
Number of SNPs coordinated: 377332
Sample size: 5422 (2787 cases, 2635 controls)
Published study: https://www.ncbi.nlm.nih.gov/pubmed/20732625
Publication year: 2010

Trait category: Mental Health
Trait: ADHD
Variable name: ADHD_PGC2017_GPS
Number of SNPs coordinated: 469352
Sample size: 55374 (20183 cases, 35191 controls)
Published study: https://www.nature.com/articles/s41588-018-0269-7
Publication year: 2017

Trait category: Mental Health
Trait: Alzheimer's Disease
Variable name: Alzheimers_Lambert2013_GPS
Number of SNPs coordinated:
Sample size: 54162 (17008 cases, 37154 controls)
Published study: https://www.nature.com/articles/ng.2802
Publication year: 2013

Trait category: Mental Health
Trait: Alzheimer's Disease family history - maternal
Variable name: AlzheimersMaternal_Marioni2018_GPS
Number of SNPs coordinated: 500706
Sample size: 314278 (27696 cases, 286582 controls)
Published study: https://www.nature.com/articles/s41398-018-0150-6
Publication year: 2018

Trait category: Mental Health
Trait: Alzheimer's Disease family history - meta-analysis of IGAP, maternal & paternal
Variable name: AlzheimersMetaIGAP_Marioni2018_GPS
Number of SNPs coordinated: 500706
Sample size: 388324 (67614 cases, 320710 controls)
Published study: https://www.nature.com/articles/s41398-018-0150-6
Publication year: 2018

Trait category: Mental Health
Trait: Alzheimer's Disease family history - parental (meta-analysis of materna & paternal)
Variable name: AlzheimersParental_Marioni2018_GPS
Number of SNPs coordinated: 500706
Sample size: 314278 (95310 cases, 218968 controls)
Published study: https://www.nature.com/articles/s41398-018-0150-6
Publication year: 2018

Trait category: Mental Health
Trait: Alzheimer's Disease family history - paternal
Variable name: AlzheimersPaternal_Marioni2018_GPS
Number of SNPs coordinated: 500706
Sample size: 314278 (14338 cases, 299940 controls)
Published study: https://www.nature.com/articles/s41398-018-0150-6
Publication year: 2018

Trait category: Mental Health
Trait: Anorexia Nervosa
Variable name: Anorexia_PGC2017_GPS
Number of SNPs coordinated: 477354
Sample size: 14477 (3495 cases, 10982 controls)
Published study: https://ajp.psychiatryonline.org/doi/abs/10.1176/appi.ajp.2017.16121402
Publication year: 2017

Trait category: Mental Health
Trait: Anxiety
Variable name: Anxiety_Purves2019_GPS
Number of SNPs coordinated: 500872
Sample size: 84217 (26104 cases, 58113 controls)
Published study: https://pubmed.ncbi.nlm.nih.gov/31748690/
Publication year: 2019

Trait category: Mental Health
Trait: Autism Spectrum Disorder
Variable name: ASD_iPsychPGC2018_GPS
Number of SNPs coordinated: 492215
Sample size: 46350 (18381 cases, 27969 controls)
Published study: https://www.nature.com/articles/s41588-019-0344-8
Publication year: 2017

Trait category: Mental Health
Trait: Autism Spectrum Disorder
Variable name: ASD_PGC2015_GPS
Number of SNPs coordinated: 498435
Sample size: 10610 (5305 cases, 5305 controls)
Published study: interim release - no publication
Publication year: 2015

Trait category: Mental Health
Trait: Autism Spectrum Disorder
Variable name: ASD_PGC2017_GPS
Number of SNPs coordinated: 456246
Sample size: 15954 (7387 cases, 8567 controls)
Published study: https://molecularautism.biomedcentral.com/articles/10.1186/s13229-017-0137-9
Publication year: 2017

Trait category: Mental Health
Trait: Bipolar Disorder
Variable name: BIP_PGC2012_GPS
Number of SNPs coordinated: 409796
Sample size: 16731 (7481 cases, 9250 controls)
Published study: https://www.ncbi.nlm.nih.gov/pubmed/21926972
Publication year: 2011

Trait category: Mental Health
Trait: Bipolar Disorder
Variable name: BIP_PGC2018_GPS
Number of SNPs coordinated: 499628
Sample size: 51710 (20352 cases, 31358 controls)
Published study: https://www.biorxiv.org/content/biorxiv/early/2018/01/24/173062.full.pdf
Publication year: 2018

Trait category: Mental Health
Trait: Depressive Symptoms
Variable name: DepressiveSympt_Okbay2016_GPS
Number of SNPs coordinated: 475871
Sample size: 161460
Published study: https://www.nature.com/articles/ng.3552#access
Publication year: 2016

Trait category: Mental Health
Trait: Ever depressed for a whole week
Variable name: Ever_depressed_for_a_whole_week_4598_UKB2017_GPS
Number of SNPs coordinated: 499422
Sample size: 109229 (58468 cases, 50761 controls)
Published study: http://www.nealelab.is/uk-biobank
Publication year: 2017

Trait category: Mental Health
Trait: Frequency of depressed mood in last 2 weeks
Variable name: Frequency_of_depressed_mood_last_2_weeks_2050_UKB2017
Number of SNPs coordinated: 499422
Sample size: 337199
Published study: http://www.nealelab.is/uk-biobank
Publication year: 2017

Trait category: Mental Health
Trait: Insomnia
Variable name: Insomnia_Jansen2018_GPS
Number of SNPs coordinated: 479925
Sample size: 386533
Published study: https://www.nature.com/articles/s41588-018-0333-3
Publication year: 2018

Trait category: Mental Health
Trait: MDD
Variable name: MDD_PGC2013_GPS
Number of SNPs coordinated: 374208
Sample size: 18759 (9240 cases, 9519 controls)
Published study: https://www.ncbi.nlm.nih.gov/pubmed/22472876
Publication year: 2013

Trait category: Mental Health
Trait: MDD
Variable name: MDD_excl23andme_PGC2018_GPS
Number of SNPs coordinated: 498245
Sample size: 173005 (59851 cases, 113154 controls)
Published study: https://www.nature.com/articles/s41588-018-0090-3
Publication year: 2018
Note: 23andme samples removed (75607 cases, 231747 controls)

Trait category: Mental Health
Trait: Non-cancer illness code, self-reported: depression
Variable name: self_reported_depression_20002_1286_UKB2017
Number of SNPs coordinated: 499422
Sample size: 337159 (19195 cases, 317964 controls)
Published study: http://www.nealelab.is/uk-biobank
Publication year: 2017

Trait category: Mental Health
Trait: OCD
Variable name: OCD_PGC2017_GPS
Number of SNPs coordinated: 498602
Sample size: 9725 (2688 cases, 7037 controls)
Published study: https://www.ncbi.nlm.nih.gov/pubmed/28761083
Publication year: 2017

Trait category: Mental Health
Trait: PTSD
Variable name: PTSD_PGC2017_GPS
Number of SNPs coordinated: 499383
Sample size: 9537 (2424 cases, 7113 controls)
Published study: https://www.nature.com/articles/mp201777
Publication year: 2017

Trait category: Mental Health
Trait: Schizophrenia
Variable name: SCZ_Pardinas2018_GPS
Number of SNPs coordinated: 487423
Sample size: 105318 (40675 cases, 64643 controls)
Published study: https://www.nature.com/articles/s41588-018-0059-2
Publication year: 2018

Trait category: Mental Health
Trait: Schizophrenia
Variable name: SCZ_PGC2012_GPS
Number of SNPs coordinated: 378036
Sample size: 21856 (9394 cases, 12462 controls)
Published study: https://www.ncbi.nlm.nih.gov/pubmed/21926974
Publication year: 2012

Trait category: Mental Health
Trait: Schizophrenia
Variable name: SCZ_PGC2014_GPS
Number of SNPs coordinated: 499197
Sample size: 82315 (35476 cases, 46839 controls)
Published study: https://www.ncbi.nlm.nih.gov/pubmed/25056061
Publication year: 2014

Trait category: Mental Health
Trait: Seen a psychiatrist for nerves, anxiety, tension or depression
Variable name: Seen_a_psychiatrist_for_nerves_etc_2100_UKB2017
Number of SNPs coordinated: 499422
Sample size: 335888 (38008 cases, 297880 controls)
Published study: http://www.nealelab.is/uk-biobank
Publication year: 2017

Trait category: Mental Health
Trait: Seen doctor (GP) for nerves, anxiety, tension or depression
Variable name: Seen_doctor_GP_for_nerves_etc_2090_UKB2017
Number of SNPs coordinated: 499422
Sample size: 335108 (115328 cases, 219780 controls)
Published study: http://www.nealelab.is/uk-biobank
Publication year: 2017

Trait category: Mental Health
Trait: Treatment/medication code: amitriptyline
Variable name: Medication_amitriptyline_20003_1140879616_UKB2017
Number of SNPs coordinated: 499422
Sample size: 337159 (6403 cases, 330756 controls)
Published study: http://www.nealelab.is/uk-biobank
Publication year: 2017

Trait category: Mental Health
Trait: Treatment/medication code: citalopram
Variable name: Medication_citalopram_20003_1140921600_UKB2017
Number of SNPs coordinated: 499422
Sample size: 337159 (5758 cases, 331401 controls)
Published study: http://www.nealelab.is/uk-biobank
Publication year: 2017

Trait category: Personality
Trait: Fed-up feelings
Variable name: fed_up_feelings_1960_UKB2017_GPS
Number of SNPs coordinated: 499422
Sample size: 330552 (134127 cases, 196425 controls)
Published study: NA
Publication year: 2017

Trait category: Personality
Trait: Guilty feelings
Variable name: guilty_feelings_2030_UKB2017_GPS
Number of SNPs coordinated: 499422
Sample size: 328769 (92945 cases, 235824 controls)
Published study: NA
Publication year: 2017

Trait category: Personality
Trait: Irritability
Variable name: irritability_1940_UKB2017_GPS
Number of SNPs coordinated: 499422
Sample size: 322668 (90282 cases, 232386 controls)
Published study: NA
Publication year: 2017

Trait category: Personality
Trait: Miserableness
Variable name: miserableness_1930_UKB2017_GPS
Number of SNPs coordinated: 499422
Sample size: 331856 (141755 cases, 190101 controls)
Published study: NA
Publication year: 2017

Trait category: Personality
Trait: Mood swings
Variable name: mood_swings_1920_UKB2017_GPS
Number of SNPs coordinated: 499422
Sample size: 329428 (148601 cases, 180827 controls)
Published study: NA
Publication year: 2017

Trait category: Personality
Trait: Morning/evening person (chronotype)
Variable name: chronotype_morning_vs_evening_1180_UKB2017_GPS
Number of SNPs coordinated: 499422
Sample size: 301143
Published study: NA
Publication year: 2017

Trait category: Personality
Trait: Neo-conscientiousness
Variable name: NEO-CONSCIENTIOUSNESS_NTR2012_GPS
Number of SNPs coordinated: 497525
Sample size: 17375
Published study: http://www.ncbi.nlm.nih.gov/pubmed/21173776
Publication year: 2012

Trait category: Personality
Trait: Neo-openness to experience
Variable name: NEO-OPENNESS_NTR2012_GPS
Number of SNPs coordinated: 436342
Sample size: 17375
Published study: http://www.ncbi.nlm.nih.gov/pubmed/21173776
Publication year: 2012

Trait category: Personality
Trait: Nervous feelings
Variable name: nervous_feelings_1970_UKB2017_GPS
Number of SNPs coordinated: 499422
Sample size: 328725 (77767 cases, 250958 controls)
Published study: NA
Publication year: 2017

Trait category: Personality
Trait: Neuroticism
Variable name: Neuroticism_SSGAC2016_GPS
Number of SNPs coordinated: 475862
Sample size: 170911
Published study: http://www.ncbi.nlm.nih.gov/pubmed/27089181
Publication year: 2016

Trait category: Personality
Trait: Neuroticism
Variable name: Neuroticism_Luciano2017_GPS
Number of SNPs coordinated: 500849
Sample size: 329821
Published study: https://www.nature.com/articles/s41588-017-0013-8
Publication year: 2017

Trait category: Personality
Trait: neuroticism score
Variable name: neuroticism_score_20127_UKB2017_GPS
Number of SNPs coordinated: 499422
Sample size: 274108
Published study: NA
Publication year: 2017

Trait category: Personality
Trait: Risk taking
Variable name: risk_taking_2040_UKB2017_GPS
Number of SNPs coordinated: 499422
Sample size: 325821 (82808 cases, 243013 controls)
Published study: NA
Publication year: 2017

Trait category: Personality
Trait: Sensitivity/hurt feelings
Variable name: sensitivity_hurt_feelings_1950_UKB2017_GPS
Number of SNPs coordinated: 499422
Sample size: 327832 (182340 cases, 145492 controls)
Published study: NA
Publication year: 2017

Trait category: Personality
Trait: Tense/highly strung
Variable name: tense_highly_strung_1990_UKB2017_GPS
Number of SNPs coordinated: 499422
Sample size: 327232 (56012 cases, 271220 controls)
Published study: NA
Publication year: 2017

Trait category: Personality
Trait: Wellbeing
Variable name: SWB_Okbay2016_GPS
Number of SNPs coordinated: 427033
Sample size: 298420
Published study: https://www.nature.com/articles/ng.3552#access
Publication year: 2016
Note: 23andme cohort not included (93,454); betas were re-calculated to remove the contribution of TEDS individuals that overlapped between discovery and target sample; original summary stats file = SWB_Full.txt.gz

Trait category: Personality
Trait: worrier/anxious feelings
Variable name: worrier_anxious_feelings_1980_UKB2017_GPS
Number of SNPs coordinated: 499422
Sample size: 328717 (186559 cases, 142158 controls)
Published study: NA
Publication year: 2017

Trait category: Personality
Trait: Worry too long after embarassment
Variable name: worry_too_long_embarassment_2000_UKB2017_GPS
Number of SNPs coordinated: 499422
Sample size: 323766 (154615 cases, 169151 controls)
Published study: NA
Publication year: 2017

Trait category: Physical Health
Trait: Angina
Variable name: Vascular_Angina_6150_2_NealeUKB2019
Number of SNPs coordinated: 433063
Sample size: 340159 (11372 cases, 349048 controls)
Published study: Neale Lab
Publication year: 2019

Trait category: Physical Health
Trait: Asthma
Variable name: Asthma_Moffatt2007_GPS
Number of SNPs coordinated: 241364
Sample size: 26475 (10365 cases, 16110 controls)
Published study: https://www.ncbi.nlm.nih.gov/pubmed/17611496
Publication year: 2007

Trait category: Physical Health
Trait: Back pain for 3+ months
Variable name: Back_pain_for_3_months_3571_UKB2017_GPS
Number of SNPs coordinated: 499422
Sample size: 84489 (57893 cases, 26596 controls)
Published study: http://www.nealelab.is/uk-biobank
Publication year: 2017

Trait category: Physical Health
Trait: Blood clot, DVT, bronchitis, emphysema, asthma, rhinitis, eczema, allergy diagnosed by doctor: Asthma
Variable name: Blood_clot_etc_6152_8_UKB2017
Number of SNPs coordinated: 499422
Sample size: 336782 (38791 cases, 297991 controls)
Published study: http://www.nealelab.is/uk-biobank
Publication year: 2017

Trait category: Physical Health
Trait: Blood clot, DVT, bronchitis, emphysema, asthma, rhinitis, eczema, allergy diagnosed by doctor: Blood clot in the leg (DVT)
Variable name: Blood_clot_etc_6152_5_UKB2017
Number of SNPs coordinated: 499422
Sample size: 336782 (6905 cases, 329877 controls)
Published study: http://www.nealelab.is/uk-biobank
Publication year: 2017

Trait category: Physical Health
Trait: Blood clot, DVT, bronchitis, emphysema, asthma, rhinitis, eczema, allergy diagnosed by doctor: Emphysema/chronic bronchitis
Variable name: Blood_clot_etc_6152_6_UKB2017
Number of SNPs coordinated: 499422
Sample size: 336782 (5599 cases, 331183 controls)
Published study: http://www.nealelab.is/uk-biobank
Publication year: 2017

Trait category: Physical Health
Trait: Blood clot, DVT, bronchitis, emphysema, asthma, rhinitis, eczema, allergy diagnosed by doctor: Hayfever, allergic rhinitis or eczema
Variable name: Blood_clot_etc_6152_9_UKB2017
Number of SNPs coordinated: 499422
Sample size: 336782 (77891 cases, 258891 controls)
Published study: http://www.nealelab.is/uk-biobank
Publication year: 2017

Trait category: Physical Health
Trait: Blood clot, DVT, bronchitis, emphysema, asthma, rhinitis, eczema, allergy diagnosed by doctor: None of the above
Variable name: Blood_clot_etc_6152_100_UKB2017
Number of SNPs coordinated: 499422
Sample size: 336782 (228530 cases, 108252 controls)
Published study: http://www.nealelab.is/uk-biobank
Publication year: 2017

Trait category: Physical Health
Trait: Bring up phlegm/sputum/mucus on most days
Variable name: Bring_up_phlegm_sputum_mucus_on_most_days_22504_UKB2017_GPS
Number of SNPs coordinated: 499422
Sample size: 83529 (6998 cases, 76531 controls)
Published study: http://www.nealelab.is/uk-biobank
Publication year: 2017

Trait category: Physical Health
Trait: Cancer code, self-reported: basal cell carcinoma
Variable name: Cancer_self_reported_BCC_20001_1061_UKB2017
Number of SNPs coordinated: 499422
Sample size: 337159 (3156 cases, 334003 controls)
Published study: http://www.nealelab.is/uk-biobank
Publication year: 2017

Trait category: Physical Health
Trait: Cancer code, self-reported: breast cancer
Variable name: Cancer_self_reported_breast_20001_1002_UKB2017
Number of SNPs coordinated: 499422
Sample size: 337159 (7480 cases, 329679 controls)
Published study: http://www.nealelab.is/uk-biobank
Publication year: 2017

Trait category: Physical Health
Trait: Cancer diagnosed by doctor
Variable name: Cancer_diagnosed_by_doctor_2453_UKB2017_GPS
Number of SNPs coordinated: 499422
Sample size: 336272 (26576 cases, 309696 controls)
Published study: http://www.nealelab.is/uk-biobank
Publication year: 2017

Trait category: Physical Health
Trait: Celiac Disease
Variable name: Celiac_Dubois2010_GPS
Number of SNPs coordinated: 226914
Sample size: 15283 (4533 cases, 10750 controls)
Published study: https://www.nature.com/articles/ng.543
Publication year: 2010

Trait category: Physical Health
Trait: Chest pain or discomfort
Variable name: Chest_pain_or_discomfort_2335_UKB2017_GPS
Number of SNPs coordinated: 499422
Sample size: 334053 (51937 cases, 282116 controls)
Published study: http://www.nealelab.is/uk-biobank
Publication year: 2017

Trait category: Physical Health
Trait: Chest pain or discomfort walking normally
Variable name: Chest_pain_or_discomfort_walking_normally_3606_UKB2017_GPS
Number of SNPs coordinated: 499422
Sample size: 51475 (8816 cases, 42659 controls)
Published study: http://www.nealelab.is/uk-biobank
Publication year: 2017

Trait category: Physical Health
Trait: Coronary Artery Disease
Variable name: CAD_Nikpay2015_GPS
Number of SNPs coordinated: 499387
Sample size: 184305 (60801 cases, 123504 controls)
Published study: https://www.ncbi.nlm.nih.gov/pubmed/26343387
Publication year: 2015

Trait category: Physical Health
Trait: Cough on most days
Variable name: Cough_on_most_days_22502_UKB2017_GPS
Number of SNPs coordinated: 499422
Sample size: 83529 (11424 cases, 72105 controls)
Published study: http://www.nealelab.is/uk-biobank
Publication year: 2017

Trait category: Physical Health
Trait: Crohns disease
Variable name: Crohns_Liu2015_GPS
Number of SNPs coordinated: 499588
Sample size: 27726 (5956 cases, 21770 controls)
Published study: https://www.nature.com/articles/ng.3359
Publication year: 2015

Trait category: Physical Health
Trait: Current employment status: Unable to work because of sickness or disability
Variable name: Unable_to_work_sickness_or_disability_6142_4_UKB2017
Number of SNPs coordinated: 499422
Sample size: 336252 (12554 cases, 323698 controls)
Published study: http://www.nealelab.is/uk-biobank
Publication year: 2017

Trait category: Physical Health
Trait: Deep Vein Thrombosis
Variable name: self_reported_dvt_20002_1094_NealeUKB2019
Number of SNPs coordinated: 433063
Sample size: 361141 (7237 cases, 353904 controls)
Published study: Neale Lab
Publication year: 2019

Trait category: Physical Health
Trait: Diabetes diagnosed by doctor
Variable name: Diabetes_diagnosed_by_doctor_2443_UKB2017_GPS
Number of SNPs coordinated: 499422
Sample size: 336473 (16183 cases, 320290 controls)
Published study: http://www.nealelab.is/uk-biobank
Publication year: 2017

Trait category: Physical Health
Trait: Diagnoses - main ICD10: C44 Other malignant neoplasms of skin
Variable name: ICD10_C44_UKB2017
Number of SNPs coordinated: 499422
Sample size: 337199 (4826 cases, 332373 controls)
Published study: http://www.nealelab.is/uk-biobank
Publication year: 2017

Trait category: Physical Health
Trait: Diagnoses - main ICD10: C50 Malignant neoplasm of breast
Variable name: ICD10_C50_UKB2017
Number of SNPs coordinated: 499422
Sample size: 337199 (5510 cases, 331689 controls)
Published study: http://www.nealelab.is/uk-biobank
Publication year: 2017

Trait category: Physical Health
Trait: Diagnoses - main ICD10: D12 Benign neoplasm of colon, rectum, anus and anal canal
Variable name: ICD10_D12_UKB2017
Number of SNPs coordinated: 499422
Sample size: 337199 (4794 cases, 332405 controls)
Published study: http://www.nealelab.is/uk-biobank
Publication year: 2017

Trait category: Physical Health
Trait: Diagnoses - main ICD10: G56 Mononeuropathies of upper limb
Variable name: ICD10_G56_UKB2017
Number of SNPs coordinated: 499422
Sample size: 337199 (5886 cases, 331313 controls)
Published study: http://www.nealelab.is/uk-biobank
Publication year: 2017

Trait category: Physical Health
Trait: Diagnoses - main ICD10: H25 Senile cataract
Variable name: ICD10_H25_UKB2017
Number of SNPs coordinated: 499422
Sample size: 337199 (2651 cases, 334548 controls)
Published study: http://www.nealelab.is/uk-biobank
Publication year: 2017

Trait category: Physical Health
Trait: Diagnoses - main ICD10: H26 Other cataract
Variable name: ICD10_H26_UKB2017
Number of SNPs coordinated: 499422
Sample size: 337199 (6025 cases, 331174 controls)
Published study: http://www.nealelab.is/uk-biobank
Publication year: 2017

Trait category: Physical Health
Trait: Diagnoses - main ICD10: I20 Angina pectoris
Variable name: ICD10_I20_UKB2017
Number of SNPs coordinated: 499422
Sample size: 337199 (4837 cases, 332362 controls)
Published study: http://www.nealelab.is/uk-biobank
Publication year: 2017

Trait category: Physical Health
Trait: Diagnoses - main ICD10: I21 Acute myocardial infarction
Variable name: ICD10_I21_UKB2017
Number of SNPs coordinated: 499422
Sample size: 337199 (3927 cases, 333272 controls)
Published study: http://www.nealelab.is/uk-biobank
Publication year: 2017

Trait category: Physical Health
Trait: Diagnoses - main ICD10: I25 Chronic ischaemic heart disease
Variable name: ICD10_I25_UKB2017
Number of SNPs coordinated: 499422
Sample size: 337199 (8755 cases, 328444 controls)
Published study: http://www.nealelab.is/uk-biobank
Publication year: 2017

Trait category: Physical Health
Trait: Diagnoses - main ICD10: I48 Atrial fibrillation and flutter
Variable name: ICD10_I48_UKB2017
Number of SNPs coordinated: 499422
Sample size: 337199 (3818 cases, 333381 controls)
Published study: http://www.nealelab.is/uk-biobank
Publication year: 2017

Trait category: Physical Health
Trait: Diagnoses - main ICD10: I80 Phlebitis and thrombophlebitis
Variable name: ICD10_I80_UKB2017
Number of SNPs coordinated: 499422
Sample size: 337199 (1613 cases, 335586 controls)
Published study: http://www.nealelab.is/uk-biobank
Publication year: 2017

Trait category: Physical Health
Trait: Diagnoses - main ICD10: I83 Varicose veins of lower extremities
Variable name: ICD10_I83_UKB2017
Number of SNPs coordinated: 499422
Sample size: 337199 (6958 cases, 330241 controls)
Published study: http://www.nealelab.is/uk-biobank
Publication year: 2017

Trait category: Physical Health
Trait: Diagnoses - main ICD10: I84 Haemorrhoids
Variable name: ICD10_I84_UKB2017
Number of SNPs coordinated: 499422
Sample size: 337199 (8190 cases, 329009 controls)
Published study: http://www.nealelab.is/uk-biobank
Publication year: 2017

Trait category: Physical Health
Trait: Diagnoses - main ICD10: K21 Gastro-oesophageal reflux disease
Variable name: ICD10_K21_UKB2017
Number of SNPs coordinated: 499422
Sample size: 337199 (7282 cases, 329917 controls)
Published study: http://www.nealelab.is/uk-biobank
Publication year: 2017

Trait category: Physical Health
Trait: Diagnoses - main ICD10: K29 Gastritis and duodenitis
Variable name: ICD10_K29_UKB2017
Number of SNPs coordinated: 499422
Sample size: 337199 (8080 cases, 329119 controls)
Published study: http://www.nealelab.is/uk-biobank
Publication year: 2017

Trait category: Physical Health
Trait: Diagnoses - main ICD10: K40 Inguinal hernia
Variable name: ICD10_K40_UKB2017
Number of SNPs coordinated: 499422
Sample size: 337199 (8815 cases, 328384 controls)
Published study: http://www.nealelab.is/uk-biobank
Publication year: 2017

Trait category: Physical Health
Trait: Diagnoses - main ICD10: K57 Diverticular disease of intestine
Variable name: ICD10_K57_UKB2017
Number of SNPs coordinated: 499422
Sample size: 337199 (6865 cases, 330334 controls)
Published study: http://www.nealelab.is/uk-biobank
Publication year: 2017

Trait category: Physical Health
Trait: Diagnoses - main ICD10: K80 Cholelithiasis
Variable name: ICD10_K80_UKB2017
Number of SNPs coordinated: 499422
Sample size: 337199 (6986 cases, 330213 controls)
Published study: http://www.nealelab.is/uk-biobank
Publication year: 2017

Trait category: Physical Health
Trait: Diagnoses - main ICD10: M16 Coxarthrosis [arthrosis of hip]
Variable name: ICD10_M16_UKB2017
Number of SNPs coordinated: 499422
Sample size: 337199 (4934 cases, 332265 controls)
Published study: http://www.nealelab.is/uk-biobank
Publication year: 2017

Trait category: Physical Health
Trait: Diagnoses - main ICD10: M17 Gonarthrosis [arthrosis of knee]
Variable name: ICD10_M17_UKB2017
Number of SNPs coordinated: 499422
Sample size: 336929 (6560 cases, 330369 controls)
Published study: http://www.nealelab.is/uk-biobank
Publication year: 2017

Trait category: Physical Health
Trait: Diagnoses - main ICD10: M54 Dorsalgia
Variable name: ICD10_M54_UKB2017
Number of SNPs coordinated: 499422
Sample size: 337199 (5660 cases, 331539 controls)
Published study: http://www.nealelab.is/uk-biobank
Publication year: 2017

Trait category: Physical Health
Trait: Diagnoses - main ICD10: M72 Fibroblastic disorders
Variable name: ICD10_M72_UKB2017
Number of SNPs coordinated: 499422
Sample size: 337199 (1862 cases, 335337 controls)
Published study: http://www.nealelab.is/uk-biobank
Publication year: 2017

Trait category: Physical Health
Trait: Diagnoses - main ICD10: R07 Pain in throat and chest
Variable name: ICD10_R07_UKB2017
Number of SNPs coordinated: 499422
Sample size: 337199 (16552 cases, 320647 controls)
Published study: http://www.nealelab.is/uk-biobank
Publication year: 2017

Trait category: Physical Health
Trait: Diagnoses - main ICD10: R10 Abdominal and pelvic pain
Variable name: ICD10_R10_UKB2017
Number of SNPs coordinated: 499422
Sample size: 337199 (14203 cases, 322996 controls)
Published study: http://www.nealelab.is/uk-biobank
Publication year: 2017

Trait category: Physical Health
Trait: Diagnoses - main ICD10: R31 Unspecified haematuria
Variable name: ICD10_R31_UKB2017
Number of SNPs coordinated: 499422
Sample size: 337199 (7363 cases, 329836 controls)
Published study: http://www.nealelab.is/uk-biobank
Publication year: 2017

Trait category: Physical Health
Trait: Doctor diagnosed asthma
Variable name: Doctor_diagnosed_asthma_22127_UKB2017
Number of SNPs coordinated: 499422
Sample size: 83529 (10589 cases, 72940 controls)
Published study: http://www.nealelab.is/uk-biobank
Publication year: 2017

Trait category: Physical Health
Trait: Doctor diagnosed hayfever or allergic rhinitis
Variable name: hayfever_or_allergic_rhinitis_22126_UKB2017
Number of SNPs coordinated: 499422
Sample size: 83529 (18934 cases, 64595 controls)
Published study: http://www.nealelab.is/uk-biobank
Publication year: 2017

Trait category: Physical Health
Trait: Eczema
Variable name: Eczema_Paternoster2015_GPS
Number of SNPs coordinated: 499077
Sample size: 116863 (21399 cases, 95464 controls)
Published study: https://www.ncbi.nlm.nih.gov/pubmed/26482879
Publication year: 2015

Trait category: Physical Health
Trait: Ever had prostate specific antigen (PSA) test
Variable name: prostate_specific_antigen_PSA_test_2365_UKB2017
Number of SNPs coordinated: 499422
Sample size: 147970 (46523 cases, 101447 controls)
Published study: http://www.nealelab.is/uk-biobank
Publication year: 2017

Trait category: Physical Health
Trait: Ever used hormone-replacement therapy (HRT)
Variable name: Ever_used_hormone_replacement_therapy_HRT__2814_UKB2017_GPS
Number of SNPs coordinated: 499422
Sample size: 180631 (71377 cases, 109254 controls)
Published study: http://www.nealelab.is/uk-biobank
Publication year: 2017

Trait category: Physical Health
Trait: Excessive daytime sleepiness
Variable name: LANE_2017_Daytime_sleepiness_GPS
Number of SNPs coordinated: 499938
Sample size: 112586
Published study: http://www.ncbi.nlm.nih.gov/pubmed/27992416
Publication year: 2017

Trait category: Physical Health
Trait: Had major operations
Variable name: Had_major_operations_2415_UKB2017_GPS
Number of SNPs coordinated: 499422
Sample size: 155045 (99647 cases, 55398 controls)
Published study: http://www.nealelab.is/uk-biobank
Publication year: 2017

Trait category: Physical Health
Trait: Had other major operations
Variable name: Had_other_major_operations_2844_UKB2017_GPS
Number of SNPs coordinated: 499422
Sample size: 179567 (120566 cases, 59001 controls)
Published study: http://www.nealelab.is/uk-biobank
Publication year: 2017

Trait category: Physical Health
Trait: HbA1C ( glycated haemoglobin)
Variable name: HbA1C_MAGIC2010_GPS
Number of SNPs coordinated: 460208
Sample size: 46368
Published study: http://www.ncbi.nlm.nih.gov/pubmed/20858683
Publication year: 2010

Trait category: Physical Health
Trait: HDL Cholesterol
Variable name: HDL_GLGC2013_GPS
Number of SNPs coordinated: 439526
Sample size: 188577
Published study: https://www.nature.com/articles/ng.2797
Publication year: 2013

Trait category: Physical Health
Trait: Headaches for 3+ months
Variable name: Headaches_for_3_months_3799_UKB2017_GPS
Number of SNPs coordinated: 499422
Sample size: 65583 (29979 cases, 35604 controls)
Published study: http://www.nealelab.is/uk-biobank
Publication year: 2017

Trait category: Physical Health
Trait: Health satisfaction
Variable name: Health_satisfaction_4548_UKB2017_GPS
Number of SNPs coordinated: 499422
Sample size: 337199
Published study: http://www.nealelab.is/uk-biobank
Publication year: 2017

Trait category: Physical Health
Trait: Hearing difficulty/problems with background noise
Variable name: Hearing_difficulty_background_noise_2257_UKB2017
Number of SNPs coordinated: 499422
Sample size: 330759 (125089 cases, 205670 controls)
Published study: http://www.nealelab.is/uk-biobank
Publication year: 2017

Trait category: Physical Health
Trait: Hearing difficulty/problems: Yes
Variable name: Hearing_difficulty_problems_2247_1_UKB2017
Number of SNPs coordinated: 499422
Sample size: 323978 (84839 cases, 239139 controls)
Published study: http://www.nealelab.is/uk-biobank
Publication year: 2017

Trait category: Physical Health
Trait: Heart attack
Variable name: Vascular_heart_problems_diagnosed_by_doctor_Heart_attack_6150_1_NealeUKB2019_GPS
Number of SNPs coordinated: 433063
Sample size: 340159 (8288 cases, 352132 controls)
Published study: Neale Lab
Publication year: 2019

Trait category: Physical Health
Trait: High blood pressure
Variable name: Vascular_heart_problems_diagnosed_by_doctor_High_blood_pressure_6150_4_NealeUKB2019_GPS
Number of SNPs coordinated: 433063
Sample size: 340159 (97139 cases, 263281 controls)
Published study: Neale Lab
Publication year: 2019

Trait category: Physical Health
Trait: Inflammatory bowel Disease
Variable name: IBD_Liu2015_GPS
Number of SNPs coordinated: 499609
Sample size: 34652 (12882 cases, 21770 controls)
Published study: https://www.nature.com/articles/ng.3359
Publication year: 2015

Trait category: Physical Health
Trait: Insomnia
Variable name: Insomnia_Hammerschlag2017_GPS
Number of SNPs coordinated: 499153
Sample size: 113006
Published study: https://www.ncbi.nlm.nih.gov/pubmed/28604731
Publication year: 2017

Trait category: Physical Health
Trait: Insomnia symptoms
Variable name: LANE_2017_Insomnia_symptoms_GPS
Number of SNPs coordinated: 499714
Sample size: 112586
Published study: http://www.ncbi.nlm.nih.gov/pubmed/27992416
Publication year: 2017

Trait category: Physical Health
Trait: LDL Cholesterol
Variable name: LDL_GLGC2013_GPS
Number of SNPs coordinated: 439052
Sample size: 188577
Published study: https://www.nature.com/articles/ng.2797
Publication year: 2013

Trait category: Physical Health
Trait: Leg pain on walking
Variable name: Leg_pain_on_walking_4728_UKB2017_GPS
Number of SNPs coordinated: 499422
Sample size: 110337 (24101 cases, 86236 controls)
Published study: http://www.nealelab.is/uk-biobank
Publication year: 2017

Trait category: Physical Health
Trait: Maternal smoking around birth
Variable name: maternal_smoking_around_birth_1787_UKB2017_GPS
Number of SNPs coordinated: 499422
Sample size: 289727 (88601 cases, 201126 controls)
Published study: NA
Publication year: 2017

Trait category: Physical Health
Trait: Medication for cholesterol, blood pressure or diabetes: Blood pressure medication
Variable name: Medication_for_cholesterol_etc_6177_2_UKB2017
Number of SNPs coordinated: 499422
Sample size: 154702 (38548 cases, 116154 controls)
Published study: http://www.nealelab.is/uk-biobank
Publication year: 2017

Trait category: Physical Health
Trait: Medication for cholesterol, blood pressure or diabetes: Cholesterol lowering medication
Variable name: Medication_for_cholesterol_etc_6177_1_UKB2017
Number of SNPs coordinated: 499422
Sample size: 154702 (35840 cases, 118862 controls)
Published study: http://www.nealelab.is/uk-biobank
Publication year: 2017

Trait category: Physical Health
Trait: Medication for cholesterol, blood pressure, diabetes, or take exogenous hormones: Blood pressure medication
Variable name: Medication_for_cholesterol_etc_6153_2_UKB2017
Number of SNPs coordinated: 499422
Sample size: 180203 (31488 cases, 148715 controls)
Published study: http://www.nealelab.is/uk-biobank
Publication year: 2017

Trait category: Physical Health
Trait: Medication for cholesterol, blood pressure, diabetes, or take exogenous hormones: Cholesterol lowering medication
Variable name: Medication_for_cholesterol_etc_6153_1_UKB2017
Number of SNPs coordinated: 499422
Sample size: 180203 (22705 cases, 157498 controls)
Published study: http://www.nealelab.is/uk-biobank
Publication year: 2017

Trait category: Physical Health
Trait: Medication for cholesterol, blood pressure, diabetes, or take exogenous hormones: Hormone replacement therapy
Variable name: Medication_for_cholesterol_etc_6153_4_UKB2017
Number of SNPs coordinated: 499422
Sample size: 180203 (13365 cases, 166838 controls)
Published study: http://www.nealelab.is/uk-biobank
Publication year: 2017

Trait category: Physical Health
Trait: Medication for cholesterol, blood pressure, diabetes, or take exogenous hormones: None of the above
Variable name: Medication_for_cholesterol_etc_6153_100_UKB2017
Number of SNPs coordinated: 499422
Sample size: 180203 (124239 cases, 55964 controls)
Published study: http://www.nealelab.is/uk-biobank
Publication year: 2017

Trait category: Physical Health
Trait: Medication for pain relief, constipation, heartburn: Aspirin
Variable name: Medication_for_pain_Aspirin_6154_1_UKB2017
Number of SNPs coordinated: 499422
Sample size: 333581 (46946 cases, 286635 controls)
Published study: http://www.nealelab.is/uk-biobank
Publication year: 2017

Trait category: Physical Health
Trait: Medication for pain relief, constipation, heartburn: Ibuprofen (e.g. Nurofen)
Variable name: Medication_for_pain_Ibuprofen_6154_2_UKB2017
Number of SNPs coordinated: 499422
Sample size: 333581 (49411 cases, 284170 controls)
Published study: http://www.nealelab.is/uk-biobank
Publication year: 2017

Trait category: Physical Health
Trait: Medication for pain relief, constipation, heartburn: Laxatives (e.g. Dulcolax, Senokot)
Variable name: Medication_for_pain_Laxatives_6154_6_UKB2017
Number of SNPs coordinated: 499422
Sample size: 333582 (9565 cases, 324017 controls)
Published study: http://www.nealelab.is/uk-biobank
Publication year: 2017

Trait category: Physical Health
Trait: Medication for pain relief, constipation, heartburn: None of the above
Variable name: Medication_for_pain_None_of_above_6154_100_UKB2017
Number of SNPs coordinated: 499422
Sample size: 333581 (184936 cases, 148645 controls)
Published study: http://www.nealelab.is/uk-biobank
Publication year: 2017

Trait category: Physical Health
Trait: Medication for pain relief, constipation, heartburn: Omeprazole (e.g. Zanprol)
Variable name: Medication_for_pain_Omeprazole_6154_5_UKB2017
Number of SNPs coordinated: 499422
Sample size: 333581 (20058 cases, 313523 controls)
Published study: http://www.nealelab.is/uk-biobank
Publication year: 2017

Trait category: Physical Health
Trait: Medication for pain relief, constipation, heartburn: Paracetamol
Variable name: Medication_for_pain_Paracetamol_6154_3_UKB2017
Number of SNPs coordinated: 499422
Sample size: 333581 (72882 cases, 260699 controls)
Published study: http://www.nealelab.is/uk-biobank
Publication year: 2017

Trait category: Physical Health
Trait: Mouth/teeth dental problems: Bleeding gums
Variable name: Mouth_etc_Bleeding_gums_6149_3_UKB2017
Number of SNPs coordinated: 499422
Sample size: 336138 (43469 cases, 292669 controls)
Published study: http://www.nealelab.is/uk-biobank
Publication year: 2017

Trait category: Physical Health
Trait: Mouth/teeth dental problems: Dentures
Variable name: Mouth_etc_Dentures_6149_6_UKB2017
Number of SNPs coordinated: 499422
Sample size: 336138 (56894 cases, 279244 controls)
Published study: http://www.nealelab.is/uk-biobank
Publication year: 2017

Trait category: Physical Health
Trait: Mouth/teeth dental problems: Loose teeth
Variable name: Mouth_etc_Loose_teeth_6149_4_UKB2017
Number of SNPs coordinated: 499422
Sample size: 336138 (13238 cases, 322900 controls)
Published study: http://www.nealelab.is/uk-biobank
Publication year: 2017

Trait category: Physical Health
Trait: Mouth/teeth dental problems: Mouth ulcers
Variable name: Mouth_etc_Mouth_ulcers_6149_1_UKB2017
Number of SNPs coordinated: 499422
Sample size: 336138 (34398 cases, 301740 controls)
Published study: http://www.nealelab.is/uk-biobank
Publication year: 2017

Trait category: Physical Health
Trait: Mouth/teeth dental problems: None of the above
Variable name: Mouth_etc_None_of_above_6149_100_UKB2017
Number of SNPs coordinated: 499422
Sample size: 336138 (204310 cases, 131828 controls)
Published study: http://www.nealelab.is/uk-biobank
Publication year: 2017

Trait category: Physical Health
Trait: Mouth/teeth dental problems: Painful gums
Variable name: Mouth_etc_Painful_gums_6149_2_UKB2017
Number of SNPs coordinated: 499422
Sample size: 336138 (9287 cases, 326851 controls)
Published study: http://www.nealelab.is/uk-biobank
Publication year: 2017

Trait category: Physical Health
Trait: Multiple Sclerosis
Variable name: MultipleSclerosis_Sawcer2011_GPS
Number of SNPs coordinated: 210382
Sample size: 27148 (9772 cases, 17376 controls)
Published study: https://www.ncbi.nlm.nih.gov/pubmed/21833088
Publication year: 2011

Trait category: Physical Health
Trait: Neck/shoulder pain for 3+ months
Variable name: Neck_shoulder_pain_for_3_months_3404_UKB2017_GPS
Number of SNPs coordinated: 499422
Sample size: 75651 (52253 cases, 23398 controls)
Published study: http://www.nealelab.is/uk-biobank
Publication year: 2017

Trait category: Physical Health
Trait: Non-cancer illness code, self-reported: angina
Variable name: self_reported_angina_20002_1074_UKB2017
Number of SNPs coordinated: 499422
Sample size: 337159 (10612 cases, 326547 controls)
Published study: http://www.nealelab.is/uk-biobank
Publication year: 2017

Trait category: Physical Health
Trait: Non-cancer illness code, self-reported: asthma
Variable name: self_reported_asthma_20002_1111_UKB2017
Number of SNPs coordinated: 499422
Sample size: 337159 (39049 cases, 298110 controls)
Published study: http://www.nealelab.is/uk-biobank
Publication year: 2017

Trait category: Physical Health
Trait: Non-cancer illness code, self-reported: back problem
Variable name: self_reported_back_problem_20002_1294_UKB2017
Number of SNPs coordinated: 499422
Sample size: 337168 (5910 cases, 331258 controls)
Published study: http://www.nealelab.is/uk-biobank
Publication year: 2017

Trait category: Physical Health
Trait: Non-cancer illness code, self-reported: cholelithiasis/gall stones
Variable name: self_reported_gall_stones_20002_1162_UKB2017
Number of SNPs coordinated: 499422
Sample size: 337159 (5573 cases, 331586 controls)
Published study: http://www.nealelab.is/uk-biobank
Publication year: 2017

Trait category: Physical Health
Trait: Non-cancer illness code, self-reported: deep venous thrombosis (dvt)
Variable name: self_reported_dvt_20002_1094_UKB2017
Number of SNPs coordinated: 499422
Sample size: 337159 (6767 cases, 330392 controls)
Published study: http://www.nealelab.is/uk-biobank
Publication year: 2017

Trait category: Physical Health
Trait: Non-cancer illness code, self-reported: diabetes
Variable name: self_reported_diabetes_20002_1220_UKB2017
Number of SNPs coordinated: 499422
Sample size: 337159 (13243 cases, 323916 controls)
Published study: http://www.nealelab.is/uk-biobank
Publication year: 2017

Trait category: Physical Health
Trait: Non-cancer illness code, self-reported: diverticular disease/diverticulitis
Variable name: self_reported_diverticular_disease_20002_1458_UKB2017
Number of SNPs coordinated: 499422
Sample size: 337159 (3840 cases, 333319 controls)
Published study: http://www.nealelab.is/uk-biobank
Publication year: 2017

Trait category: Physical Health
Trait: Non-cancer illness code, self-reported: eczema/dermatitis
Variable name: self_reported_eczema_dermatitis_20002_1452_UKB2017
Number of SNPs coordinated: 499422
Sample size: 337159 (8718 cases, 328441 controls)
Published study: http://www.nealelab.is/uk-biobank
Publication year: 2017

Trait category: Physical Health
Trait: Non-cancer illness code, self-reported: emphysema/chronic bronchitis
Variable name: self_reported_emphysema_bronchitis_20002_1113_UKB2017
Number of SNPs coordinated: 499422
Sample size: 337159 (4573 cases, 332586 controls)
Published study: http://www.nealelab.is/uk-biobank
Publication year: 2017

Trait category: Physical Health
Trait: Non-cancer illness code, self-reported: glaucoma
Variable name: self_reported_glaucoma_20002_1277_UKB2017
Number of SNPs coordinated: 499422
Sample size: 337159 (3536 cases, 333623 controls)
Published study: http://www.nealelab.is/uk-biobank
Publication year: 2017

Trait category: Physical Health
Trait: Non-cancer illness code, self-reported: gout
Variable name: self_reported_gout_20002_1466_UKB2017
Number of SNPs coordinated: 499422
Sample size: 337159 (4807 cases, 332352 controls)
Published study: http://www.nealelab.is/uk-biobank
Publication year: 2017

Trait category: Physical Health
Trait: Non-cancer illness code, self-reported: hayfever/allergic rhinitis
Variable name: self_reported_hayfever_etc_20002_1387_UKB2017
Number of SNPs coordinated: 499422
Sample size: 337159 (19320 cases, 317839 controls)
Published study: http://www.nealelab.is/uk-biobank
Publication year: 2017

Trait category: Physical Health
Trait: Non-cancer illness code, self-reported: heart attack/myocardial infarction
Variable name: self_reported_heart_attack_etc_20002_1075_UKB2017
Number of SNPs coordinated: 499422
Sample size: 337159 (7735 cases, 329424 controls)
Published study: http://www.nealelab.is/uk-biobank
Publication year: 2017

Trait category: Physical Health
Trait: Non-cancer illness code, self-reported: hiatus hernia
Variable name: self_reported_hiatus_hernia_20002_1474_UKB2017
Number of SNPs coordinated: 499422
Sample size: 337159 (7865 cases, 329294 controls)
Published study: http://www.nealelab.is/uk-biobank
Publication year: 2017

Trait category: Physical Health
Trait: Non-cancer illness code, self-reported: hyperthyroidism/thyrotoxicosis
Variable name: self_reported_hyperthyroidism_20002_1225_UKB2017
Number of SNPs coordinated: 499422
Sample size: 337159 (2547 cases, 334612 controls)
Published study: http://www.nealelab.is/uk-biobank
Publication year: 2017

Trait category: Physical Health
Trait: Non-cancer illness code, self-reported: hypothyroidism/myxoedema
Variable name: self_reported_hypothyroidism_20002_1226_UKB2017
Number of SNPs coordinated: 499422
Sample size: 337159 (16376 cases, 320783 controls)
Published study: http://www.nealelab.is/uk-biobank
Publication year: 2017

Trait category: Physical Health
Trait: Non-cancer illness code, self-reported: kidney stone/ureter stone/bladder stone
Variable name: self_reported_kidney_stone_etc_20002_1197_UKB2017
Number of SNPs coordinated: 499422
Sample size: 337159 (2694 cases, 334465 controls)
Published study: http://www.nealelab.is/uk-biobank
Publication year: 2017

Trait category: Physical Health
Trait: Non-cancer illness code, self-reported: migraine
Variable name: self_reported_migraine_20002_1265_UKB2017
Number of SNPs coordinated: 499422
Sample size: 337159 (10007 cases, 327152 controls)
Published study: http://www.nealelab.is/uk-biobank
Publication year: 2017

Trait category: Physical Health
Trait: Non-cancer illness code, self-reported: osteoarthritis
Variable name: self_reported_osteoarthritis_20002_1465_UKB2017
Number of SNPs coordinated: 499422
Sample size: 337159 (28257 cases, 308902 controls)
Published study: http://www.nealelab.is/uk-biobank
Publication year: 2017

Trait category: Physical Health
Trait: Non-cancer illness code, self-reported: osteoporosis
Variable name: self_reported_osteoporosis_20002_1309_UKB2017
Number of SNPs coordinated: 499422
Sample size: 337159 (5266 cases, 331893 controls)
Published study: http://www.nealelab.is/uk-biobank
Publication year: 2017

Trait category: Physical Health
Trait: Non-cancer illness code, self-reported: psoriasis
Variable name: self_reported_psoriasis_20002_1453_UKB2017
Number of SNPs coordinated: 499422
Sample size: 337159 (3871 cases, 333288 controls)
Published study: http://www.nealelab.is/uk-biobank
Publication year: 2017

Trait category: Physical Health
Trait: Number of operations, self-reported
Variable name: Number_of_operations_self_reported_136_UKB2017_GPS
Number of SNPs coordinated: 499422
Sample size: 337199
Published study: http://www.nealelab.is/uk-biobank
Publication year: 2017

Trait category: Physical Health
Trait: Number of self-reported cancers
Variable name: Number_of_self_reported_cancers_134_UKB2017_GPS
Number of SNPs coordinated: 499422
Sample size: 337199
Published study: http://www.nealelab.is/uk-biobank
Publication year: 2017

Trait category: Physical Health
Trait: Number of self-reported non-cancer illnesses
Variable name: Number_of_self_reported_non_cancer_135_UKB2017
Number of SNPs coordinated: 499422
Sample size: 337199
Published study: http://www.nealelab.is/uk-biobank
Publication year: 2017

Trait category: Physical Health
Trait: Number of treatments/medications taken
Variable name: Number_of_treatments_medications_taken_137_UKB2017_GPS
Number of SNPs coordinated: 499422
Sample size: 337199
Published study: http://www.nealelab.is/uk-biobank
Publication year: 2017

Trait category: Physical Health
Trait: Osteoporosis (heel bone mineral density)
Variable name: BoneMinDen_Kemp2017_GPS
Number of SNPs coordinated: 499989
Sample size: 142487
Published study: https://www.nature.com/articles/ng.3949
Publication year: 2017
Note: summary stats formatted because LDpred cannot handle very small pvalues (pval less than 0.00000001 recoded as 0.00000001)

Trait category: Physical Health
Trait: Other serious medical condition/disability diagnosed by doctor
Variable name: Other_serious_diagnosed_by_doctor_2473_UKB2017
Number of SNPs coordinated: 499422
Sample size: 331274 (67968 cases, 263306 controls)
Published study: http://www.nealelab.is/uk-biobank
Publication year: 2017
Note: reverse sign

Trait category: Physical Health
Trait: Overall health rating
Variable name: Overall_health_rating_2178_UKB2017_GPS
Number of SNPs coordinated: 499422
Sample size: 337199
Published study: http://www.nealelab.is/blog/2017/7/19/rapid-gwas-of-thousands-of-phenotypes-for-337000-samples-in-the-uk-biobank
Publication year: 2017
Note: reverse sign

Trait category: Physical Health
Trait: Pain type(s) experienced in last month: Back pain
Variable name: Recent_Back_pain_6159_4_UKB2017
Number of SNPs coordinated: 499422
Sample size: 336650 (85221 cases, 251429 controls)
Published study: http://www.nealelab.is/uk-biobank
Publication year: 2017

Trait category: Physical Health
Trait: Pain type(s) experienced in last month: Facial pain
Variable name: Recent_Facial_pain_6159_2_UKB2017
Number of SNPs coordinated: 499422
Sample size: 336650 (6118 cases, 330532 controls)
Published study: http://www.nealelab.is/uk-biobank
Publication year: 2017

Trait category: Physical Health
Trait: Pain type(s) experienced in last month: Headache
Variable name: Recent_Headache_6159_1_UKB2017
Number of SNPs coordinated: 499422
Sample size: 336650 (66967 cases, 269683 controls)
Published study: http://www.nealelab.is/uk-biobank
Publication year: 2017

Trait category: Physical Health
Trait: Pain type(s) experienced in last month: Hip pain
Variable name: Recent_Hip_pain_6159_6_UKB2017
Number of SNPs coordinated: 499422
Sample size: 336650 (37714 cases, 298936 controls)
Published study: http://www.nealelab.is/uk-biobank
Publication year: 2017

Trait category: Physical Health
Trait: Pain type(s) experienced in last month: Knee pain
Variable name: Recent_Knee_pain_6159_7_UKB2017
Number of SNPs coordinated: 499422
Sample size: 336650 (71561 cases, 265089 controls)
Published study: http://www.nealelab.is/uk-biobank
Publication year: 2017

Trait category: Physical Health
Trait: Pain type(s) experienced in last month: Neck or shoulder pain
Variable name: Recent_Neck_or_shoulder_pain_6159_3_UKB2017
Number of SNPs coordinated: 499422
Sample size: 336650 (76404 cases, 260246 controls)
Published study: http://www.nealelab.is/uk-biobank
Publication year: 2017

Trait category: Physical Health
Trait: Pain type(s) experienced in last month: None of the above
Variable name: Recent_None_of_the_above_6159_100_UKB2017
Number of SNPs coordinated: 499422
Sample size: 336650 (136199 cases, 200451 controls)
Published study: http://www.nealelab.is/uk-biobank
Publication year: 2017

Trait category: Physical Health
Trait: Pain type(s) experienced in last month: Pain all over the body
Variable name: Recent_Pain_all_over_the_body_6159_8_UKB2017
Number of SNPs coordinated: 499422
Sample size: 336650 (5099 cases, 331551 controls)
Published study: http://www.nealelab.is/uk-biobank
Publication year: 2017

Trait category: Physical Health
Trait: Pain type(s) experienced in last month: Stomach or abdominal pain
Variable name: Recent_Stomach_or_abdominal_pain_6159_5_UKB2017
Number of SNPs coordinated: 499422
Sample size: 336650 (28098 cases, 308552 controls)
Published study: http://www.nealelab.is/uk-biobank
Publication year: 2017

Trait category: Physical Health
Trait: Parkinson's disease
Variable name: Parkinsons_SimonSanchez2009_GPS
Number of SNPs coordinated: 210404
Sample size: 5691 (1713 cases, 3978 controls)
Published study: https://www.ncbi.nlm.nih.gov/pubmed?cmd=DetailsSearch&term=19915575%5BPMID%5D
Publication year: 2009

Trait category: Physical Health
Trait: primary biliary cirrhosis
Variable name: PrimaryBiliaryCirrhosis_Cordell2015_GPS
Number of SNPs coordinated: 358509
Sample size: 13239 (2764 cases, 10475 controls)
Published study: https://www.ncbi.nlm.nih.gov/pubmed/26394269
Publication year: 2015

Trait category: Physical Health
Trait: Resting Heart Rate
Variable name: RestHeartRate_Eppinga_GPS
Number of SNPs coordinated: 450000
Sample size: 265046
Published study: https://www.nature.com/articles/ng.3708
Publication year: 2016

Trait category: Physical Health
Trait: Rheumatoid Arthritis
Variable name: RA_Okada2014_GPS
Number of SNPs coordinated: 494198
Sample size: 103638 (29880 cases, 73758 controls)
Published study: https://www.ncbi.nlm.nih.gov/pubmed/24390342
Publication year: 2014

Trait category: Physical Health
Trait: Self-rated Health
Variable name: SRH_Hill2016_GPS
Number of SNPs coordinated: 499990
Sample size: 111749
Published study: https://academic.oup.com/ije/article/46/3/994/2670320
Publication year: 2016

Trait category: Physical Health
Trait: Sleep disorders
Variable name: ICD10_G47_UKB2017
Number of SNPs coordinated: 499425
Sample size: 337199
Published study: http://www.nealelab.is/blog/2017/7/19/rapid-gwas-of-thousands-of-phenotypes-for-337000-samples-in-the-uk-biobank
Publication year: 2017

Trait category: Physical Health
Trait: sleep duration
Variable name: sleep_duration_1160_UKB2017_GPS
Number of SNPs coordinated: 499422
Sample size: 128266
Published study: NA
Publication year: 2017

Trait category: Physical Health
Trait: Sleeplessness / insomnia
Variable name: Sleeplessness___insomnia_1200_UKB2017_GPS
Number of SNPs coordinated: 499422
Sample size: 337199
Published study: http://www.nealelab.is/uk-biobank
Publication year: 2017

Trait category: Physical Health
Trait: systemic lupus erythematosus
Variable name: Lupus_Bentham2015_GPS
Number of SNPs coordinated: 395436
Sample size: 23210 (7219 cases, 15991 controls)
Published study: https://www.ncbi.nlm.nih.gov/pubmed/26502338
Publication year: 2015

Trait category: Physical Health
Trait: Taking other prescription medications
Variable name: Taking_other_prescription_medications_2492_UKB2017_GPS
Number of SNPs coordinated: 499422
Sample size: 336330 (158113 cases, 178217 controls)
Published study: http://www.nealelab.is/uk-biobank
Publication year: 2017

Trait category: Physical Health
Trait: Tinnitus: Yes, now most or all of the time
Variable name: Tinnitus_4803_11_UKB2017
Number of SNPs coordinated: 499422
Sample size: 109411 (7214 cases, 102197 controls)
Published study: http://www.nealelab.is/uk-biobank
Publication year: 2017

Trait category: Physical Health
Trait: Treatment/medication code: alendronate sodium
Variable name: Medication_alendronate_20003_1140922174_UKB2017
Number of SNPs coordinated: 499422
Sample size: 337159 (3773 cases, 333386 controls)
Published study: http://www.nealelab.is/uk-biobank
Publication year: 2017

Trait category: Physical Health
Trait: Treatment/medication code: allopurinol
Variable name: Medication_allopurinol_20003_1140875408_UKB2017
Number of SNPs coordinated: 499422
Sample size: 337139 (3819 cases, 333320 controls)
Published study: http://www.nealelab.is/uk-biobank
Publication year: 2017

Trait category: Physical Health
Trait: Treatment/medication code: amlodipine
Variable name: Medication_amlodipine_20003_1140879802_UKB2017
Number of SNPs coordinated: 499422
Sample size: 337159 (13693 cases, 323466 controls)
Published study: http://www.nealelab.is/uk-biobank
Publication year: 2017

Trait category: Physical Health
Trait: Treatment/medication code: aspirin
Variable name: Medication_aspirin_20003_1140868226_UKB2017
Number of SNPs coordinated: 499422
Sample size: 337159 (45012 cases, 292147 controls)
Published study: http://www.nealelab.is/uk-biobank
Publication year: 2017

Trait category: Physical Health
Trait: Treatment/medication code: atenolol
Variable name: Medication_atenolol_20003_1140866738_UKB2017
Number of SNPs coordinated: 499422
Sample size: 337159 (13184 cases, 323975 controls)
Published study: http://www.nealelab.is/uk-biobank
Publication year: 2017

Trait category: Physical Health
Trait: Treatment/medication code: atorvastatin
Variable name: Medication_atorvastatin_20003_1141146234_UKB2017
Number of SNPs coordinated: 499422
Sample size: 337159 (10167 cases, 326992 controls)
Published study: http://www.nealelab.is/uk-biobank
Publication year: 2017

Trait category: Physical Health
Trait: Treatment/medication code: bendroflumethiazide
Variable name: Medication_bendroflumethiazide_20003_1141194794_UKB2017
Number of SNPs coordinated: 499422
Sample size: 337159 (19084 cases, 318075 controls)
Published study: http://www.nealelab.is/uk-biobank
Publication year: 2017

Trait category: Physical Health
Trait: Treatment/medication code: cetirizine
Variable name: Medication_cetirizine_20003_1140883504_UKB2017
Number of SNPs coordinated: 499422
Sample size: 337159 (3821 cases, 333338 controls)
Published study: http://www.nealelab.is/uk-biobank
Publication year: 2017

Trait category: Physical Health
Trait: Treatment/medication code: co-codamol
Variable name: Medication_co_codamol_20003_1140923346_UKB2017
Number of SNPs coordinated: 499422
Sample size: 337159 (7861 cases, 329298 controls)
Published study: http://www.nealelab.is/uk-biobank
Publication year: 2017

Trait category: Physical Health
Trait: Treatment/medication code: diclofenac
Variable name: Medication_diclofenac_20003_1140884488_UKB2017
Number of SNPs coordinated: 499422
Sample size: 337159 (7116 cases, 330043 controls)
Published study: http://www.nealelab.is/uk-biobank
Publication year: 2017

Trait category: Physical Health
Trait: Treatment/medication code: doxazosin
Variable name: Medication_doxazosin_20003_1140879778_UKB2017
Number of SNPs coordinated: 499422
Sample size: 337159 (3803 cases, 333356 controls)
Published study: http://www.nealelab.is/uk-biobank
Publication year: 2017

Trait category: Physical Health
Trait: Treatment/medication code: enalapril
Variable name: Medication_enalapril_20003_1140888552_UKB2017
Number of SNPs coordinated: 499422
Sample size: 337159 (2626 cases, 334533 controls)
Published study: http://www.nealelab.is/uk-biobank
Publication year: 2017

Trait category: Physical Health
Trait: Treatment/medication code: furosemide
Variable name: Medication_furosemide_20003_1140909708_UKB2017
Number of SNPs coordinated: 499422
Sample size: 337159 (2539 cases, 334620 controls)
Published study: http://www.nealelab.is/uk-biobank
Publication year: 2017

Trait category: Physical Health
Trait: Treatment/medication code: gliclazide
Variable name: Medication_gliclazide_20003_1140874744_UKB2017
Number of SNPs coordinated: 499422
Sample size: 337159 (2807 cases, 334352 controls)
Published study: http://www.nealelab.is/uk-biobank
Publication year: 2017

Trait category: Physical Health
Trait: Treatment/medication code: glucosamine product
Variable name: Medication_glucosamine_20003_1141188442_UKB2017
Number of SNPs coordinated: 499422
Sample size: 337159 (22914 cases, 314245 controls)
Published study: http://www.nealelab.is/uk-biobank
Publication year: 2017

Trait category: Physical Health
Trait: Treatment/medication code: ibuprofen
Variable name: Medication_ibuprofen_20003_1140871310_UKB2017
Number of SNPs coordinated: 499422
Sample size: 337159 (41952 cases, 295207 controls)
Published study: http://www.nealelab.is/uk-biobank
Publication year: 2017

Trait category: Physical Health
Trait: Treatment/medication code: insulin product
Variable name: Medication_insulin_product_20003_1140883066_UKB2017
Number of SNPs coordinated: 499422
Sample size: 337159 (3319 cases, 333840 controls)
Published study: http://www.nealelab.is/uk-biobank
Publication year: 2017

Trait category: Physical Health
Trait: Treatment/medication code: lisinopril
Variable name: Medication_lisinopril_20003_1140860696_UKB2017
Number of SNPs coordinated: 499422
Sample size: 337159 (9393 cases, 327766 controls)
Published study: http://www.nealelab.is/uk-biobank
Publication year: 2017

Trait category: Physical Health
Trait: Treatment/medication code: metformin
Variable name: Medication_metformin_20003_1140884600_UKB2017
Number of SNPs coordinated: 499422
Sample size: 337159 (8392 cases, 328767 controls)
Published study: http://www.nealelab.is/uk-biobank
Publication year: 2017

Trait category: Physical Health
Trait: Treatment/medication code: omeprazole
Variable name: Medication_omeprazole_20003_1140865634_UKB2017
Number of SNPs coordinated: 499422
Sample size: 337159 (19668 cases, 317491 controls)
Published study: http://www.nealelab.is/uk-biobank
Publication year: 2017

Trait category: Physical Health
Trait: Treatment/medication code: paracetamol
Variable name: Medication_paracetamol_20003_2038460150_UKB2017
Number of SNPs coordinated: 499422
Sample size: 337159 (62050 cases, 275109 controls)
Published study: http://www.nealelab.is/uk-biobank
Publication year: 2017

Trait category: Physical Health
Trait: Treatment/medication code: perindopril
Variable name: Medication_perindopril_20003_1140888560_UKB2017
Number of SNPs coordinated: 499422
Sample size: 337159 (4822 cases, 332337 controls)
Published study: http://www.nealelab.is/uk-biobank
Publication year: 2017

Trait category: Physical Health
Trait: Treatment/medication code: ramipril
Variable name: Medication_ramipril_20003_1140860806_UKB2017
Number of SNPs coordinated: 499422
Sample size: 337159 (15787 cases, 321372 controls)
Published study: http://www.nealelab.is/uk-biobank
Publication year: 2017

Trait category: Physical Health
Trait: Treatment/medication code: salbutamol
Variable name: Medication_salbutamol_20003_1140881856_UKB2017
Number of SNPs coordinated: 499422
Sample size: 337159 (3972 cases, 333187 controls)
Published study: http://www.nealelab.is/uk-biobank
Publication year: 2017

Trait category: Physical Health
Trait: Treatment/medication code: symbicort 100/6 turbohaler
Variable name: Medication_symbicort_20003_1141174520_UKB2017
Number of SNPs coordinated: 499422
Sample size: 337159 (2089 cases, 335070 controls)
Published study: http://www.nealelab.is/uk-biobank
Publication year: 2017

Trait category: Physical Health
Trait: Treatment/medication code: thyroxine product
Variable name: Medication_thyroxine_product_20003_1140884516_UKB2017
Number of SNPs coordinated: 499422
Sample size: 337159 (3917 cases, 333242 controls)
Published study: http://www.nealelab.is/uk-biobank
Publication year: 2017

Trait category: Physical Health
Trait: Treatment/medication code: tramadol
Variable name: Medication_tramadol_20003_1140864992_UKB2017
Number of SNPs coordinated: 499422
Sample size: 337159 (3724 cases, 333435 controls)
Published study: http://www.nealelab.is/uk-biobank
Publication year: 2017

Trait category: Physical Health
Trait: Treatment/medication code: ventolin 100micrograms inhaler
Variable name: Medication_ventolin_20003_1140861998_UKB2017
Number of SNPs coordinated: 499422
Sample size: 337159 (9712 cases, 327447 controls)
Published study: http://www.nealelab.is/uk-biobank
Publication year: 2017

Trait category: Physical Health
Trait: Treatment/medication code: warfarin
Variable name: Medication_warfarin_20003_1140888266_UKB2017
Number of SNPs coordinated: 499422
Sample size: 337159 (3404 cases, 333755 controls)
Published study: http://www.nealelab.is/uk-biobank
Publication year: 2017

Trait category: Physical Health
Trait: Type 2 Diabetes
Variable name: T2Diabetes_Scott2017_GPS
Number of SNPs coordinated: 499770
Sample size: 159208 (26676 cases, 132532 controls)
Published study: https://www.ncbi.nlm.nih.gov/pubmed/28566273
Publication year: 2017

Trait category: Physical Health
Trait: Ulcerative colitis
Variable name: Colitis_Liu2015_GPS
Number of SNPs coordinated: 499593
Sample size: 28738 (6968 cases, 21770 controls)
Published study: https://www.nature.com/articles/ng.3359
Publication year: 2015

Trait category: Physical Health
Trait: Used an inhaler for chest within last hour
Variable name: Used_an_inhaler_3090_UKB2017
Number of SNPs coordinated: 499422
Sample size: 309688 (2245 cases, 307443 controls)
Published study: http://www.nealelab.is/uk-biobank
Publication year: 2017

Trait category: Physical Health
Trait: Vascular/heart problems diagnosed by doctor: Angina
Variable name: Vascular_Angina_6150_2_UKB2017
Number of SNPs coordinated: 499422
Sample size: 336683 (10618 cases, 326065 controls)
Published study: http://www.nealelab.is/uk-biobank
Publication year: 2017

Trait category: Physical Health
Trait: Vascular/heart problems diagnosed by doctor: Heart attack
Variable name: Vascular_Heart_attack_6150_1_UKB2017
Number of SNPs coordinated: 499422
Sample size: 336683 (7790 cases, 328893 controls)
Published study: http://www.nealelab.is/uk-biobank
Publication year: 2017

Trait category: Physical Health
Trait: Vascular/heart problems diagnosed by doctor: High blood pressure
Variable name: Vascular_High_blood_pressure_6150_4_UKB2017
Number of SNPs coordinated: 499422
Sample size: 336683 (91033 cases, 245650 controls)
Published study: http://www.nealelab.is/uk-biobank
Publication year: 2017

Trait category: Physical Health
Trait: Vascular/heart problems diagnosed by doctor: None of the above
Variable name: Vascular_None_of_the_above_6150_100_UKB2017
Number of SNPs coordinated: 499422
Sample size: 336683 (236530 cases, 100153 controls)
Published study: http://www.nealelab.is/uk-biobank
Publication year: 2017

Trait category: Physical Health
Trait: Wheeze or whistling in the chest in last year
Variable name: Wheeze_or_whistling_in_the_chest_in_last_year_2316_UKB2017_GPS
Number of SNPs coordinated: 499422
Sample size: 331257 (68531 cases, 262726 controls)
Published study: http://www.nealelab.is/uk-biobank
Publication year: 2017

Trait category: SES
Trait: Household Income
Variable name: Income_Hill2016_GPS
Number of SNPs coordinated: 499990
Sample size: 112151
Published study: https://www.sciencedirect.com/science/article/pii/S0960982216311198
Publication year: 2016

Trait category: SES
Trait: Social Deprivation (Townsend Index)
Variable name: SocDepriv_Hill2016_GPS
Number of SNPs coordinated: 499990
Sample size: 112151
Published study: https://www.sciencedirect.com/science/article/pii/S0960982216311198
Publication year: 2016

Trait category: SES
Trait: Townsend deprivation index
Variable name: townsend_dep_index_20189_UKB2017_GPS
Number of SNPs coordinated: 499422
Sample size: 336798
Published study: NA
Publication year: 2017